chemical mediators for MCQ

1_ a 15 years old girl has had ebisodes of sneezing with watery eyes,running nose for the past 2 weeks . on physical esmination . she has red ,swollen mucosal surfaces . she has had similar episodes each spring and winter . her syptomes are most likely to be mediated by the release of which of the following mediators

a_complet c3a
b_ platelet activating factor
c_ T.N.F
d_histamine
e_IgG

2_ a22 years old man develops marked right lower quadrant abdominal pain over the past day . laparascopic surgery is performed and the appendix is swllen , erthematous and partly covered by a yellowish exudate . it is removed and a microscopic section show infiltration with numerous PNLs , the resulting pain result
from which of the chemical mediators

a_complent c3a & IgG
b_IL1
c_seretonin
d_PG &bradykinin
e_c5a & IL8

3_ a20 years old man has exprienced painful urination for 4 days . a urethritis is suspected . numerous PNLs are present in aswear of the exudate from the urethra . these PNLs undergoes chemotaxis to reach the organism. release of which of the following chemical mediators is most likely to drive PNLs

a_histamine
b_prostaglandin
c_NO
d_bradykinin
e_c5a

4_a35 years old woman has been taking acetylsalicylic acid for fever for the past 4 days . her fever is temporarly reduced via the therpay . this fever reduction is most likely to be the result of which of the chemical mediators

a_c5a
b_IL1
c_prostaglandin
d_bradykinin
e_seretonin

5_the role of PG in acute inflamation include

a_leukocyte pavementation
b_Rolling
c_Tissue damage
d_transmigration
e_none of the above

6_a patient suffers pharyngeal infection of 3 days duration with fever and chils on physical examination . there is swelling,erthema and phayngeal &purulent exudate , which type of inflammation does he have

a_granulamatous inflammation
b_acute non suppurative inflammation
c_abcess formation
d_resolution of inflammation
e_chronic inflammation

7_whithin minutes following abee sting , a37 years old man develops marked dysnea .he also develops swelling , erthemia seen in his arms andlegs . which of the following C. M is most important in pathogenisis of this condition

a_bradykinin
b_c5a
c_NO
d_T.N.F
e_histamine

8_chemotaxis is mediated by

a_histamine
b_IL6
c_c3a
d_selectin
e_intergrin

9_Rolling with transient adhesion of leukocyte to vascular endothelium is mediated by
a_IL8
b_IL6
c_selectin
d_itegrin
e_TNF

10_ which of the following is correct regaring to acnte inflammation

a_it may be trigged by histamine
b_it has a rapid response specific to the nature of the injury
c_it always heals by resolution