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من طرف snow_white الأحد أغسطس 15, 2010 10:10 am
[size=18]BIOCHEMISTRY
QUESTIONS
Proteins:
1.Define:Iso-electric point, zwitter ion,chaperons,antigen,epitope,hapten.
2.give an example for: semi-essential AAs,mixed AAs,non protein AAs,cu containing enzyme.
3.compare between α-helix and β pleated chains.
4.Define chaperons,and discuss their functions.
5.Discuss protein denaturation and its effects.
6.compare between Hb and Mb.
7.Discuss structure of different Hb physiological forms.
8.Define 2,3BPG and its function.
9.Discuss sickle cell anaemia on bases of geneticdefect and its effect.
10.compare between collagen and elastin.
11.Discuss 2 different methods of protein separation.
12.Illustrate diagrammatically structure of monomeric immunoglobulin
13.compare between IgG,IgM,IgA.
14.Compare between primary and secondary immune responses.
15.discuss biologically important membrane proteins.
Enzymes:
16. Define: Apo-enzyme, Co-enzyme, substrate, rate of reaction, Zymogens,ribozymes,isoenzymes,metalloenzymes.
17. Enumerate major classes of enzymes giving examples.
18. Discuss enzyme catalytic activity.
19. Write what do you know about specificity of enzyme catalysis.
20. Enumerate factors affecting rate of enzymatic reactions.
21. Define Km and its importance.
22. Write down 3 co-enzymes derived from vitamins.
23. compare between different types of enzyme inhibition giving examples whenever possible. .
24. Discuss briefly Enzyme regulation:long term,short term,hormonal
25. Discuss role of non-functional enzymes clinically giving examples.
26. Write what do you know about Isozymes,giving examples.
27. Discuss role of enzymes as therapeutic and diagnostic agents.
Vitamins :
28. Write what do you about vitamin A importance and deficiency.
29. Vitamin D is considered as a hormone rather than a vitamin.Comment.
30. Discuss importance and deficiency manifestations of Vit.D.
31. Discuss importance of Vit . E .
32. Enumerate biomedical role of Vit . K.
33. Discuss biomedical functions and deficiency of Vit. C .
34. Discuss causes vitamin C deficiency associated anaemia.
35. Define : Beri-beri
36. Define: Pellagra.
37. Define: Pernicious anaemia.,folate trap.
38.Mention 3 vitamins,their derived co-enzymes,and their def.manifest.
39.Discuss Werinke-Korsakkoff Syndrome.
40.Enumerate vitamin def causing anaemia,dermatitis.
Carbohydrates
:
41.Define:Enantiomerism,epimerism,anomerism,mutaro tation,…
42.give example for: sugar alcohol,deoxy sugar,sulfated glycosaminglycans,….
43.Enumerate different types of carbohydrates isomers giving examples.
44.Mention biologically important pentoses.
45.Compare between glycogen,starch and cellulose.
46.compare between dextrins and dextrans.
47.Enumerate sulfated glycosaminglycans.
48.Discuss proteoglycans structure and function.
49.compare between laminin and fibronectin.
50.Discuss glyproteins structure and functions.
Lipids:
51.Give examples for ω3 and ω6 Fatty acids and their examples.
52.discuss Eicosanoinds ,their structure and functions.
53.compare between Glycogen and TAG as a storage form of energy.
54.Enumerate different types of glycerophospholipids and their importance.
55.Define trepenes and their function.
56.discuss free radicals, structure , and damage produced by them.
57.discuss lipid peroxidation and its phases.
58.Define mode of action of different types of anti-oxidants.
59.Discuss biomedical importance of free radicals study.
60.Discuss inborn membrane structure defects.
Molecular biology :
61.Define: vector, cosmid, plasmid, telomere, PCR, operon, genetic-code, Tm, prion, Histones, gene, genome, okazaki fragments,cyclins,apoptosis,caspases,replication fork,replisomes,SSBP,transcription bubble,ribozymes,reverse transcriptase,proofreading,primer,cDNA, restriction endonucleaes,Taq polymerase,promoter,wobble rule,frame shift mutation,excision repair,housekeeping genes,leading strand ,lagging strand,topoisomerases.
62.Mention biologically active nucleotides and their functions.
63.Discuss base methylation and its functions.
64.Compare between DNA and RNA.
65.Discuss initiation ,elongation,or termination of replication
66. Discuss initiation ,elongation,or termination of transcription.
67. Discuss initiation ,elongation,or termination of translation.
69.Discuss post-transcription processing.
70. Discuss post-translation processing.
71.Discuss lac operon.(prokaryotic gene expression regulation)
72.compare between replication and transcription.
73.discuss biochemical sequence of apoptosis .
74.enumearte different types of tumor markers.
75.discuss different types of DNA mutations and repair.
G☺☺D LUCK
.................................................. .........
snow_white- مــراقــب قـسـم
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تاريخ التسجيل : 03/07/2010
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The Editor- الإدارة
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تاريخ التسجيل : 24/08/2010
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