ReVision on hiStologY - MCQ

Question 1. CELL MEMBRANE


(a) is structurally based on a lipid bilayer - True False

(b) contains proteins which only act as enzymes - True False

(c) surrounds the nucleus in a single layer - True False

(d) surrounds individual ribosomeswithin the cell - True False

(e) is maintained by vesicles derived from the Golgi - True False





Question 2. LYSOSOMES


(a) lysosomes have a membrane H+-ATPase capable of maintaining an acid environment - True False

(b) the enzymes contained in lysosomes are also present in peroxisomes - True False

(c) vesicles from the Golgi take acid hydrolases to lysosomes - True False

(d) fusion of an endosome with a vesicle containing acid hydrolases forms an endolysosome - True False

(e) lysosomal storage diseases are caused by lack of specific lysosomal enzymes leading to accumulation of a metabolic product - True False






Question 3. IN DIVIDING CELLS


(a) the nuclear membrane is fragmented during separation of chromosomes - True False

(b) the nucleolus is involved in ribosomal biogenesis and is a prominent structure in dividing cells - True False

(c) prophase and metaphase both occur in the S phase of the cell cycle - True False

(d) the final daughter cells which derive from meiosis are haploid - True False

(e) control of the overall population may be regulated by apoptosis - True False






Question 4. THERE ARE SEVERAL DISTINCT FEATURES OF EPITHELIAL CELLS:


(a) squamous epithelial cells are flat and plate-like - True False

(b) a pseudostratified epithelium has all its cells in contact with the underlying extracellular matrix - True False

(c) a simple columnar cell is typically 2-3 times higher than its width - True False

(d) cell division occurs at all layers in a stratified squamous epithelium - True False

(e) transitional epithelium is a characteristic cell lining the urinary tract - True False







Question 5. IN EPITHELIAL CELLS:


(a) microvilli are braced by the actin cytoskeleton - True False

(b) membrane plaques are a feature of transitional epithelium - True False

(c) cilia are based on the intermediate filaments - True False

(d) the glycocalyx is seen within the rough ER and stores lipids - True False

(e) the characteristic type of intermediate filament is cytokeratin - True False







Question 6. COLLAGEN


(a) type I is the main collagen in skin - True False

(b) type IV is the main type in bone - True False

(c) type III is the main type in reticulin - True False

(d) is secreted by fibroblasts as procollagen molecules. - True False

(e) is one of the matrix components of osteoid. - True False







Question 7. BASEMENT MEMBRANE


(a) contains type I collagen - True False

(b) contains laminin - True False

(c) contains glycosaminoglycans - True False

(d) links to epithelial cells via integrin receptors - True False

(e) acts as a permeability barrier. - True False






Question 8. SKELETAL MUSCLE CELLS


(a) have thin filaments made of actin which are anchored to the Z band - True False

(b) have thick filaments made of desmin which are anchored to the M band - True False

(c) regulate contraction by control of calcium release from sarcoplasmic reticulum - True False

(d) are surrounded by an external lamina - True False

(e) contain multiple nuclei in each cell - True False